Deal Flow
Letter · prints on one page
Transaction tear sheetData as of Nov 7, 2026
M&A · Healthcare · Pharmaceutical Preparations

BioCryst Pharmaceuticals Inc to acquire Astria Therapeutics, Inc.

Announced Oct 14, 2025 · Closed Jan 23, 2026

Deal value$920MEV $657M
Premium53.0%To unaffected price
EV / Adj. EBITDA—
ConsiderationCash and stock$13.00 per share

Transaction

Acquirer
BioCryst Pharmaceuticals Inc (BCRX)
Target
Astria Therapeutics, Inc. (ATXS)
Buyer type
Strategic
Offer price per share
$13.00
Enterprise value
$657M
Status
Closed Jan 23, 2026

Deal protections

Break fee (target pays)
$32.3M · 3.5%
Reverse fee (buyer pays)
—
Go-shop
No-shop
Financing
—

Advisors

To the acquirer
BofA Securities
To the target
Evercore
Evercore fee
$23.0M

Sector context · Healthcare

Comparable deals
93 in the prior 24 months
Premium
53.0% vs. 63.5% sector median
EV / Adj. EBITDA
Sector median 15.9x
Break fee
3.5% vs. 3.3% sector median

Timeline

  1. AnnouncedOct 14, 2025
  2. Proxy filedDec 18, 2025
  3. Definitive proxyDec 18, 2025
  4. Shareholder voteJan 21, 2026
  5. ClosedJan 23, 2026

Valuation · fairness opinions

Discounted cash flow$12.60$16.75
Discounted cash flow$14.15$14.70
Analyst price targets$20.00$49.00
Premiums paid$12.40$16.60
Discounted cash flow$10.60$11.70
Offer $13.00

Implied value per Astria Therapeutics, Inc. share by analysis, from Evercore · DCF discount rate 13%–16%.

Sources
  • 8-K (EX-99.2) · Oct 14, 2025
  • 425 (EX-99.2) · Oct 14, 2025

Adj. EBITDA is operating income + D&A + impairment, restructuring, deal costs and stock compensation, less any large gain on a sale, last twelve months, from the target's filings. Calculated by Castle, so it can differ from a bank's adjusted figure.

Prepared with Castle from public SEC EDGAR filings. Figures are extracted automatically; verify against the source documents. Not investment advice.