Deal Flow
Letter · prints on one page
Transaction tear sheetData as of Nov 7, 2026
M&A · Healthcare · Services-Medical Laboratories

Tempus AI, Inc. to acquire Personalis, Inc.

Announced Jul 20, 2026 · Pending Aug 31, 2026

Deal value$1.50BEV $1.50B
Premium6.0%To unaffected price
EV / Adj. EBITDA—23.3x EV / Revenue
ConsiderationCash and stock$16.25 per share

Transaction

Acquirer
Tempus AI, Inc. (TEM)
Target
Personalis, Inc. (PSNL)
Buyer type
Strategic
Offer price per share
$16.25
Enterprise value
$1.50B
Status
Pending Aug 31, 2026

Deal protections

Break fee (target pays)
$76.8M · 5.1%
Reverse fee (buyer pays)
$76.8M · 5.1%
Go-shop
No-shop
Financing
No financing condition

Advisors

To the acquirer
Not disclosed
To the target
Centerview, TD Cowen, Morgan Stanley
Centerview fee
$29.4M
TD Cowen fee
$15.0M

Sector context · Healthcare

Comparable deals
101 in the prior 24 months
Premium
6.0% vs. 49.0% sector median
EV / Adj. EBITDA
Sector median 10.9x
Break fee
5.1% vs. 3.5% sector median

Timeline

  1. AnnouncedJul 20, 2026
  2. Proxy filedOct 21, 2026
  3. Definitive proxyOct 21, 2026
  4. Shareholder votePending
  5. ClosedPending

Valuation · fairness opinions

Trading comparablesCenterview$8.95$14.15
Precedent transactionsCenterview$7.75$16.05
Discounted cash flowCenterview$11.05$16.75
Analyst price targetsCenterview$10.00$18.00
Premiums paidCenterview$16.15$22.75
Trading comparablesTD Cowen$6.17$13.29
Trading comparablesTD Cowen$7.80$16.66
Precedent transactionsTD Cowen$5.66$10.81
Precedent transactionsTD Cowen$7.31$14.41
Discounted cash flowTD Cowen$10.56$12.65
Offer $16.25

Implied value per Personalis, Inc. share by analysis, from Centerview and TD Cowen · DCF discount rate 16.5%–19%.

Sources
  • 8-K (EX-99.1) · Jul 20, 2026
  • 8-K (EX-99.1) · Jul 20, 2026
  • 425 · Jul 20, 2026
  • 425 · Jul 20, 2026
  • 425 · Jul 20, 2026
  • 8-K · Jul 20, 2026

Adj. EBITDA is operating income + D&A + impairment, restructuring, deal costs and stock compensation, less any large gain on a sale, last twelve months, from the target's filings. Calculated by Castle, so it can differ from a bank's adjusted figure.

Prepared with Castle from public SEC EDGAR filings. Figures are extracted automatically; verify against the source documents. Not investment advice.