Deal Flow
Letter · prints on one page
Transaction tear sheetData as of Nov 7, 2026
M&A · Healthcare · Pharmaceutical Preparations

Ipsen, S.A. to acquire Epizyme, Inc.

Announced Jun 27, 2022 · Closed Aug 12, 2022

Deal value$247MEV $378M
Premium53.0%To unaffected price
EV / Adj. EBITDA—9.8x EV / Revenue
ConsiderationAll cash$1.45 per share

Transaction

Acquirer
Ipsen, S.A.
Target
Epizyme, Inc.
Buyer type
Strategic
Offer price per share
$1.45
Enterprise value
$378M
Status
Closed Aug 12, 2022

Deal protections

Break fee (target pays)
$9.9M · 4.0%
Reverse fee (buyer pays)
—
Go-shop
No-shop
Financing
No financing condition

Advisors

To the acquirer
Barclays
To the target
Jefferies, MTS Health Partners
MTS Health Partners fee
$5.7M

Sector context · Healthcare

Comparable deals
48 in the prior 24 months
Premium
53.0% vs. 46.5% sector median
EV / Adj. EBITDA
Sector median 20.4x
Break fee
4.0% vs. 3.4% sector median

Timeline

  1. AnnouncedJun 27, 2022
  2. Tender offerJul 12, 2022
  3. ClosedAug 12, 2022

Valuation · fairness opinions

Other analysis$0.63$2.66
Discounted cash flow$0.20$1.95
Discounted cash flow$1.35$2.50
Trading comparables$0.25$0.90
Trading comparables$0.25$2.50
Offer $1.45

Implied value per Epizyme, Inc. share by analysis, from MTS Health Partners.

Sources
  • 8-K (EX-99) · Jun 27, 2022
  • SC14D9C (EX-99.1) · Jun 27, 2022
  • 8-K · Jun 27, 2022
  • SC TO-C (EX-99.2) · Jul 5, 2022

Adj. EBITDA is operating income + D&A + impairment, restructuring, deal costs and stock compensation, less any large gain on a sale, last twelve months, from the target's filings. Calculated by Castle, so it can differ from a bank's adjusted figure.

Prepared with Castle from public SEC EDGAR filings. Figures are extracted automatically; verify against the source documents. Not investment advice.