Deal Flow
Letter · prints on one page
Transaction tear sheetData as of Nov 7, 2026
M&A · Healthcare · Pharmaceutical Preparations

Novartis AG to acquire Avidity Biosciences, Inc.

Announced Oct 26, 2025 · Closed Feb 27, 2026

Deal value$12.00BEV $9.02B
Premium46.0%To unaffected price
EV / Adj. EBITDA—
ConsiderationAll cash$72.00 per share

Transaction

Acquirer
Novartis AG (NVS)
Target
Avidity Biosciences, Inc. (RNA)
Buyer type
Strategic
Offer price per share
$72.00
Enterprise value
$9.02B
Status
Closed Feb 27, 2026

Deal protections

Break fee (target pays)
$450M · 3.8%
Reverse fee (buyer pays)
$600M · 5.0%
Go-shop
No-shop
Financing
—

Advisors

To the acquirer
Not disclosed
To the target
Goldman Sachs, Barclays

Sector context · Healthcare

Comparable deals
96 in the prior 24 months
Premium
46.0% vs. 59.5% sector median
EV / Adj. EBITDA
Sector median 14.5x
Break fee
3.8% vs. 3.3% sector median

Timeline

  1. AnnouncedOct 26, 2025
  2. Proxy filedNov 24, 2025
  3. Definitive proxyJan 30, 2026
  4. Shareholder voteFeb 26, 2026
  5. ClosedFeb 27, 2026

Valuation · fairness opinions

Analyst price targetsGoldman Sachs$66.00$79.00
Precedent transactionsGoldman Sachs$67.00$80.00
Discounted cash flowBarclays$63.87$75.36
Premiums paidBarclays$67.00$84.00
52-week trading rangeBarclays$62.00$77.00
Analyst price targetsBarclays$53.00$96.00
Offer $72.00

Implied value per Avidity Biosciences, Inc. share by analysis, from Goldman Sachs and Barclays · DCF discount rate 15%–17%.

Sources
  • 8-K (EX-99) · Oct 27, 2025
  • DEFA14A (EX-99.1) · Oct 27, 2025
  • 8-K · Oct 27, 2025
  • DEFA14A · Oct 27, 2025
  • 8-K (EX-99.1) · Nov 10, 2025
  • DEFA14A · Nov 10, 2025

Adj. EBITDA is operating income + D&A + impairment, restructuring, deal costs and stock compensation, less any large gain on a sale, last twelve months, from the target's filings. Calculated by Castle, so it can differ from a bank's adjusted figure.

Prepared with Castle from public SEC EDGAR filings. Figures are extracted automatically; verify against the source documents. Not investment advice.