Deal Flow
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Transaction tear sheetData as of Nov 7, 2026
M&A · Healthcare · Pharmaceutical Preparations

Vertex Pharmaceuticals Inc to acquire Alpine Immune Sciences, Inc.

Announced Apr 10, 2024 · Closed May 20, 2024

Deal value$4.90BEV $4.86B
Premium67.0%To unaffected price
EV / Adj. EBITDA—
ConsiderationAll cash$65.00 per share

Transaction

Acquirer
Vertex Pharmaceuticals Inc (VRTX)
Target
Alpine Immune Sciences, Inc.
Buyer type
Strategic
Offer price per share
$65.00
Enterprise value
$4.86B
Status
Closed May 20, 2024

Deal protections

Break fee (target pays)
$173M · 3.5%
Reverse fee (buyer pays)
—
Go-shop
No-shop
Financing
No financing condition

Advisors

To the acquirer
Lazard
To the target
Centerview
Centerview fee
$60.0M

Sector context · Healthcare

Comparable deals
108 in the prior 24 months
Premium
67.0% vs. 53.0% sector median
EV / Adj. EBITDA
Sector median 17.1x
Break fee
3.5% vs. 3.5% sector median

Timeline

  1. AnnouncedApr 10, 2024
  2. Tender offerApr 22, 2024
  3. ClosedMay 20, 2024

Valuation · fairness opinions

Discounted cash flow$51.75$63.80
Analyst price targets$41.00$55.00
52-week trading range$54.50$66.20
52-week trading range$52.00$60.30
Offer $65.00

Implied value per Alpine Immune Sciences, Inc. share by analysis, from Centerview · DCF discount rate 12%–14%.

Sources
  • 8-K (EX-99) · Apr 10, 2024
  • SC14D9C (EX-99.1) · Apr 10, 2024
  • 8-K · Apr 10, 2024
  • 8-K (EX-99.1) · May 9, 2024

Adj. EBITDA is operating income + D&A + impairment, restructuring, deal costs and stock compensation, less any large gain on a sale, last twelve months, from the target's filings. Calculated by Castle, so it can differ from a bank's adjusted figure.

Prepared with Castle from public SEC EDGAR filings. Figures are extracted automatically; verify against the source documents. Not investment advice.