Deal Flow
Letter · prints on one page
Transaction tear sheetData as of Nov 7, 2026
M&A · Healthcare · Pharmaceutical Preparations

Vertex Pharmaceuticals Inc to acquire Crinetics Pharmaceuticals, Inc.

Announced Jul 6, 2026 · Closed Sep 1, 2026

Deal value$10.00BEV $9.89B
Premium101.0%To unaffected price
EV / Adj. EBITDA—
ConsiderationAll cash$85.00 per share

Transaction

Acquirer
Vertex Pharmaceuticals Inc (VRTX)
Target
Crinetics Pharmaceuticals, Inc. (CRNX)
Buyer type
Strategic
Offer price per share
$85.00
Enterprise value
$9.89B
Status
Closed Sep 1, 2026

Deal protections

Break fee (target pays)
$350M · 3.5%
Reverse fee (buyer pays)
—
Go-shop
No-shop
Financing
Committed · BofA Securities, Morgan Stanley

Advisors

To the acquirer
Morgan Stanley, Lazard
To the target
JPMorgan, Leerink Partners

Sector context · Healthcare

Comparable deals
98 in the prior 24 months
Premium
101.0% vs. 49.0% sector median
EV / Adj. EBITDA
Sector median 10.9x
Break fee
3.5% vs. 3.5% sector median

Timeline

  1. AnnouncedJul 6, 2026
  2. Proxy filedJul 21, 2026
  3. Definitive proxyJul 31, 2026
  4. Shareholder voteAug 28, 2026
  5. ClosedSep 1, 2026

Valuation · fairness opinions

Trading comparablesJPMorgan$30.75$95.00
Other analysisJPMorgan$47.75$84.75
Discounted cash flowJPMorgan$68.25$86.00
Analyst price targetsJPMorgan$55.00$97.00
Analyst price targetsJPMorgan$49.25$87.00
Discounted cash flowLeerink Partners$68.20$86.02
Precedent transactionsLeerink Partners$73.59$99.34
Precedent transactionsLeerink Partners$47.81$65.01
Premiums paidLeerink Partners$59.39$80.15
Analyst price targetsLeerink Partners$55.00$97.00
Offer $85.00

Implied value per Crinetics Pharmaceuticals, Inc. share by analysis, from JPMorgan and Leerink Partners · DCF discount rate 10.5%–12.5%.

Sources
  • 8-K (EX-99.1) · Jul 6, 2026
  • DEFA14A · Jul 6, 2026
  • 8-K · Jul 10, 2026
  • 8-K (EX-99.1) · Aug 3, 2026

Adj. EBITDA is operating income + D&A + impairment, restructuring, deal costs and stock compensation, less any large gain on a sale, last twelve months, from the target's filings. Calculated by Castle, so it can differ from a bank's adjusted figure.

Prepared with Castle from public SEC EDGAR filings. Figures are extracted automatically; verify against the source documents. Not investment advice.