Deal Flow
Letter · prints on one page
Transaction tear sheetData as of Nov 7, 2026
M&A · Healthcare · Pharmaceutical Preparations

Pfizer Inc to acquire Metsera, Inc.

Announced Sep 22, 2025 · Closed Nov 13, 2025

Deal value$4.90BEV $4.90B
Premium43.0%To unaffected price
EV / Adj. EBITDA—
ConsiderationAll cash$47.50 per share

Transaction

Acquirer
Pfizer Inc (PFE)
Target
Metsera, Inc. (MTSR)
Buyer type
Strategic
Offer price per share
$47.50
Enterprise value
$4.90B
Status
Closed Nov 13, 2025

Deal protections

Break fee (target pays)
$190M · 3.9%
Reverse fee (buyer pays)
—
Go-shop
No-shop
Financing
No financing condition

Advisors

To the acquirer
Citigroup
To the target
Guggenheim, Goldman Sachs
Guggenheim fee
$30.0M

Sector context · Healthcare

Comparable deals
95 in the prior 24 months
Premium
43.0% vs. 67.0% sector median
EV / Adj. EBITDA
Sector median 14.5x
Break fee
3.9% vs. 3.3% sector median

Timeline

  1. AnnouncedSep 22, 2025
  2. Proxy filedOct 6, 2025
  3. Definitive proxyOct 17, 2025
  4. Shareholder voteNov 12, 2025
  5. ClosedNov 13, 2025

Valuation · fairness opinions

Discounted cash flowGoldman Sachs$39.76$49.85
Premiums paidGoldman Sachs$46.65$64.97
Discounted cash flowGuggenheim$41.09$51.52
Discounted cash flowGuggenheim$47.31$62.97
Analyst price targetsGuggenheim$46.93$72.28
Offer $47.50

Implied value per Metsera, Inc. share by analysis, from Goldman Sachs and Guggenheim · DCF discount rate 13%–15%.

Sources
  • 8-K (EX-99) · Sep 22, 2025
  • 8-K · Sep 22, 2025
  • 8-K · Nov 10, 2025
  • DEFA14A · Nov 10, 2025

Adj. EBITDA is operating income + D&A + impairment, restructuring, deal costs and stock compensation, less any large gain on a sale, last twelve months, from the target's filings. Calculated by Castle, so it can differ from a bank's adjusted figure.

Prepared with Castle from public SEC EDGAR filings. Figures are extracted automatically; verify against the source documents. Not investment advice.